Animal models that reproduce human diseases are important for various disease research as well as drug development. Genome editing tools based on the CRISPR-Cas9 system are a breakthrough technology that allows the precise introduction of mutations at the target DNA sequences. The development of CRISPR-Cas9 technology has accelerated the creation of animal models and greatly facilitated related research. The development of the clustered regularly interspaced short palindromic repeats (CRISPR) system has enabled a faster and cheaper production of animal models compared with traditional methods.

Creative Biogene utilizes the CRISPR-Cas9 system to provide gene editing and model development services for a variety of model animals, including mice, rats, zebrafish, C.elegans, and many other species. Our experienced gene editing team, combined with our advanced technology platform, is dedicated to creating stable gene modification programs in animals, including knockouts, point mutations, short insertions, knock-ins and conditional knock-ins. We use a variety of technologies and strategies to provide customized solutions to our clients' demands in order to accelerate their relevant basic research and drug development processes.

Gene Editing Animal Model Generation Service at Creative Biogene

Creative Biogene offers a comprehensive range of services, including model animal selection and customization of gene modification strategies. With the power of CRISPR, we are able to efficiently and accurately modify animal genomes, enabling researchers to gain insights into gene function, disease mechanisms and potential therapeutic interventions.

Model selection

Creative Biogene's platform offers a wide selection of models, including mouse, rat, zebrafish, C.elegans, etc., which are suitable for different aspects of genetic research. Our experienced researchers work closely with clients to understand their research demands and combine the features and advantages of different models to select the most suitable animal model for the next step of genetic modification.